Role of chloroquine as an anticancer agent
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چکیده
منابع مشابه
Potential Role of Garcinol as an Anticancer Agent
Garcinol, a polyisoprenylated benzophenone, is extracted from the rind of the fruit of Garcinia indica, a plant found extensively in tropical regions. Although the fruit has been consumed traditionally over centuries, its biological activities, specifically its anticancer potential is a result of recent scientific investigations. The anticarcinogenic properties of garcinol appear to be moderate...
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Itraconazole, a common anti-fungal agent, has demonstrated potential anticancer activity, including reversing chemoresistance mediated by P-glycoprotein, modulating the signal transduction pathways of Hedgehog, mechanistic target of rapamycin and Wnt/β-catenin in cancer cells, inhibiting angiogenesis and lymphangiogenesis, and possibly interfering with cancer-stromal cell interactions. Clinical...
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The objective of the article is to highlight various roles of glutamic acid like endogenic anticancer agent, conjugates to anticancer agents, and derivatives of glutamic acid as possible anticancer agents. Besides these emphases are given especially for two endogenous derivatives of glutamic acid such as glutamine and glutamate. Glutamine is a derivative of glutamic acid and is formed in the bo...
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Hydroxamic acids serve as a monsulfhydril bisubstrate analog inhibition of fernesyl protein transferase (FPT), the enzyme catalysing fernesylation of p21ras. Tumor necrosis factor (TFN) is specifically prevented by synthetic hydroxamic acid-based metalloproteinase inhibitors. Suberoyanilide hydroxamic acid (SAHA) have been identified as histone deacetylase inhibitors based on their ability to i...
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ژورنال
عنوان ژورنال: International Journal of Research in Pharmaceutical Sciences
سال: 2018
ISSN: 0975-7538
DOI: 10.26452/ijrps.v9i1.1214